The aim of the project is to attract human resources to science by forming an interdisciplinary group in systems biology, in which computer modelers and experimenters will cooperate.

Research direction: development, optimization and application of dynamic, quantitative computer models in yeast and bacterial metabolic engineering, design of biotechnological processes and development of their control. The experiments will not be based on descriptive notions of the metabolism of microorganisms, but on detailed computer models of metabolism.

Project No. 2009/0207/1DP/

Source of funding: European Structural Fund

Project period: 01.12.2009.  – 30.11.2012

Projcet budget: 1 900 000 EUR

Project coordinator: Professor Egils Stalidzans

Project participant from group: Senior researcher, Agris Pentjušs,


  • Institute of Microbiology and Biotechnology, University of Latvia (Uldis Kalnenieks)
  • Faculty of Information and Communication Technologies, Latvia University of Life Sciences and Technologies, Jelgava, Latvia (Egils Stalidzans)
  • Faculty of Material Science and Applied Chemistry, Riga Technical University, Riga, Latvia (Juris Vanags)


Pentjuss, Agris, & Kalnenieks, U. (2013). Assessment of Zymomonas mobilis biotechnological potential in ethanol production by flux variability analysis. Biosystems and Information Technology, 3(1), 1–5.

Pentjuss, A., Odzina, I., Kostromins, A., Fell, D. A., Stalidzans, E., & Kalnenieks, U. (2013). Biotechnological potential of respiring Zymomonas mobilis: A stoichiometric analysis of its central metabolism. Journal of Biotechnology, 165(1).